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(2R)-2-Deoxy-2-Fluoro-2-Methyl-D-Erythropentonic Acid Gamma-Lactone 3,5-Dibenzoate | SFBM | C20H17FO6 | CAS 874638-80-9

  • Product Name: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
  • CAS: 874638-80-9
  • MF: C20H17FO6
  • MW: 372.35
  • EINECS: 618-021-4
  • Product Categories: apis;Sofosbuvir intermediate
  • Mol File: 874638-80-9.mol
  • Origin: China

    Property

    Melting point: 133℃
    Boiling point: 458.6±34.0 °C
    Density: 1.33
    Storage temp.: 2-8°C

    Application

    Neuromuscular blocking agent
    (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1''-C-cyano-2''-fluoro-2''-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
    ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate is an impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.

    Package And Storage

    Package: 
    25kg/carton drum or as your requirements.
    Remark: Chemical composition and size can be optimized by the customers' requirements固体16gs固体2ys0

     Storage:
    Separated from ammonium nitrate and potassium chlorate. Dry.Keep container tightly closed in a dry and well-ventilated place. Hygroscopic.

    Safety Protection

    Precautions for safe handling
    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

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